Document ID (ISN) | 38322 |
CIS number |
82-1646 |
ISSN - Serial title |
Staub |
Year |
1981 |
Convention or series no. |
|
Author(s) |
Marshall M. |
Title |
Effects of low carbon monoxide concentrations on the cardiovascular system |
Original title |
Wirkungen niedriger Kohlenmonoxidkonzentrationen auf das Herzkreislaufsystem [in German] |
Bibliographic information |
Aug. 1981, Vol.41, No.8, p.296-300. Illus. 34 ref. |
Abstract |
The possible modification of the threshold limit value for carbon monoxide is discussed with a review of current knowledge as to the effects of low CO concentrations (equivalent to a maximum COHb level of 6%) on the cardiovascular system: mechanism of blood oxygen transport inhibition, incidence of CO in industry, animal experiments and human studies. COHb levels between 3 and 10% produce functional lesions; higher levels (9-15%) produce morphological lesions in the cardiovascular system. The threshold limit value for CO should be such that the COHb level remains 3% in order to eliminate all possible hazard. Review of relevant factors such as the method of determining CO and COHb levels, the objective of the threshold limit value, the type of exposure, the species of animal, and smoking. |
Descriptors (primary) |
threshold limit values; blood circulation; carboxyhaemoglobin level; carbon monoxide |
Descriptors (secondary) |
animal experiments; biological effects; human experiments |
Document type |
D - Periodical articles |
Subject(s) |
Occupational pathology
|
Broad subject area(s) |
|
Browse category(ies) |
Blood diseases Cardiovascular diseases Carbon monoxide Inorganic substances Occupational exposure limits
|