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Document ID (ISN)38312
CIS number 82-1598
ISSN - Serial title 0096-1736 - Journal of Occupational Medicine
Year 1981
Convention or series no.
Author(s) Karol M.H.
Title Survey of industrial workers for antibodies to toluene diisocyanate
Bibliographic information Nov. 1981, Vol.23, No.11, p.741-747. Illus. 22 ref.
Abstract Screening programme of 103 workers exposed 6-24 months to tolylene diisocyanate (TDI) concentrations <0.02ppm; 20 of the workers had acute exposures to TDI as a result of spills or splashes. Antibody responses by radioallergosorbent (RAST) test were observed only in some of the workers with an acute exposure history, and particularly in those whose acute exposure was accompanied by immediate respiratory symptoms and a decrease in FEV1 of 20% or greater. RAST test may be of value in routine serologic screening as an early warning of developing TDI hypersensitivity.
Descriptors (primary) allergens; allergic reactivity; immunology; tolylene diisocyanate
Descriptors (secondary) functional respiratory disorders; immuno-allergy; exposure tests; allergy tests; radioallergosorbent test
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Allergies
Isocyanates
Cyano compounds