| Document ID (ISN) | 38269 |
| CIS number |
82-1396 |
| ISSN - Serial title |
0003-9896 - Archives of Environmental Health |
| Year |
1981 |
| Convention or series no. |
|
| Author(s) |
Murray T., Walker B.R., Spratt D.M., Chappelka R. |
| Title |
Cadmium nephropathy: Monitoring for early evidence of renal dysfunction |
| Bibliographic information |
July-Aug. 1981, Vol.36, No.4, p.165-171. 25 ref. |
| Abstract |
In an attempt to establish a screening method for early detection of cadmium-induced nephropathy at a reversible stage, periodic analyses of cadmium (Cd) level were determined in the blood, urine, and hair of 23 workers exposed to platics and pigments containing a Cd stabiliser. Urine cytology, creatinine clearance and urinary levels of lysozyme, β-2-microglobulins, immunoglobulins and aminoacids were also monitored. Cd levels in blood and urine were only useful as indicators of acute environmental exposure. Hair Cd content was elevated in most workers. Urine cytology was not reliable as an indicator of possible nephropathy. All 5 measures of renal function are recommended in screening and follow-up of Cd workers. |
| Descriptors (primary) |
renal dysfunction; cadmium; exposure tests; nephrotoxic effects |
| Descriptors (secondary) |
amino acids; lysozymes; urinary electrolyte changes; immunoglobulin changes; pigments; creatinine excretion; blood monitoring; urine monitoring; urine cytology; determination in hair; plastics industry |
| Document type |
D - Periodical articles |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
|
| Browse category(ies) |
Inorganic substances
Biological monitoring
Diseases of the kidney and the urinary system
Cadmium and compounds
|
