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Document ID (ISN)37658
CIS number 82-798
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1981
Convention or series no.
Author(s) Chmielnicka J., Komsta-Szumska E., Szymańska J.A.
Title Arginase and kallikrein activities as biochemical indices of occupational exposure to lead
Bibliographic information May 1981, Vol.38, No.2, p.175-178. Illus. 26 ref.
Abstract Urine lead concentration (Pb-U), blood Pb concentration (Pb-B), haematocrit, δ-aminolaevulinic acid dehydratase (ALAD) and arginase activities, and urinary ALA and coproporphyrin (CP) concentrations, and kallikrein activity were determined in 60 Pb-exposed workers. Correlation coefficients of -0.78 and 0.77 for Pb-B/ALAD and Pb-B/arginase were found respectively for Pb/B >40g/dl, and 0.82, 0.76,-0.74 and -0.64 for Pb-U/ALA, Pb-U/Cp-U, Pb-U/kallikrein, and ALA/kallikrein, respectively. An increase in serum arginase activity may indicate liver damage, while a decrease in kallikrein activity may indicate kidney damage in Pb-exposed workers.
Descriptors (primary) lead; exposure tests; enzyme disturbances
Descriptors (secondary) hepatic damage; arginase; ALAD; kidney; urinary ala monitoring; blood monitoring; urine monitoring; serum changes
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Inorganic substances
Biological monitoring
Blood diseases
Lead and compounds