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Document ID (ISN)37585
CIS number 82-822
ISSN - Serial title 0028-4793 - New England Journal of Medicine
Year 1982
Convention or series no.
Author(s) Senanayake N., Johnson M.K.
Title Acute polyneuropathy after poisoning by a new organophosphate insecticide
Bibliographic information 21 Jan. 1982, Vol.306, No.3, p.155-157. 7 ref.
Abstract In 3 of 10 cases described, accidental exposure to Tamaron occurred as a result of agricultural spraying operations. Patients had an acute cholinergic crisis soon after exposure and polyneuropathy developed 2-3 weeks later. No prior evidence of polyneuropathy associated with Tamaron, or the active ingredient methamidophos (MP) exists. No evidence of impurity involvement in the polyneuropathy was found and alterations in the pharmacokinetics of MP are implicated as a result of preliminary experiments with hens.
Descriptors (primary) organophosphorus compounds; insecticides; tamaron; crop protection; polyneuritis
Descriptors (secondary) acute poisoning; case study; agriculture; animal experiments; organic thiophosphates
Document type D - Periodical articles
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s)
Browse category(ies) Diseases of the nervous system
Esters and salts
Agricultural chemicals