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CISDOC database

Document ID (ISN)37546
CIS number 82-772
ISSN - Serial title 0049-8610 - Zeitschrift für die gesamte Hygiene und ihre Grenzgebiete
Year 1981
Convention or series no.
Author(s) Klein G., Gromadies B., Bürger A., Scheunert E., Rittner G.
Title Effects of long-term exposure to carbon disulfide and halogenated hydrocarbons, especially perchloroethylene, on lipid metabolism
Original title Langzeitwirkungen von Schwefelkohlenstoff und Halogenkohlenwasserstoffen, besonders Perchloräthylen, auf den Fettstoffwechsel [in German]
Bibliographic information Jan. 1981, Vol.27, No.1, p.48-51. 21 ref.
Abstract Comparative study of 111 workers exposed to CS2 (222 controls) and 189 workers exposed to halogenated hydrocarbons (378 controls). A significantly increased rate of lipid metabolism changes (42.3%) was found in the CS2-exposed persons; in the group exposed to halogenated hydrocarbons, the hyperlipoproteinaemia rate was 13.2%. Correlations were established between the β-lipoproteins, tri-glycerides and cholesterol, and the results of other laboratory tests. The positive correlations between the Broca index, lipoproteins and cholesterol were most marked in those exposed to CS2. The pathology of changes in lipid metabolism and standard biological values (lipoproteins in particular) due to halogenated hydrocarbons and CS2 is discussed.
Descriptors (primary) tetrachloroethylene; halogenated hydrocarbons; metabolic disturbances; lipids; hyperlipaemia; carbon disulfide
Descriptors (secondary) lipoproteins; exposure tests; long-term exposure; cholesterol
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Inorganic substances
Halogenated hydrocarbons
Endocrine diseases
Blood diseases
Inorganic sulfur compounds