|Document ID (ISN)||37536|
|ISSN - Serial title
||Gigiena truda i professional'nye zabolevanija
|Convention or series no.
||The pathogenic effects of mixed dust generated in cadmium production
||K ocenke patogennogo dejstvija pyli kadmievogo proizvodstva [in Russian]|
||Dec. 1980, No.12, p.39-41.
||Rats inhaling mixed dust from copper and cadmium ore concentrates (10mg/m3 and 2mg/m3) were studied by physiological, biochemical and pathomorphological methods to detect toxic and fibrogenic effects. Apart from functional impairments, the inner organs, examined morphologically after one month of exposure, showed inflammatory changes due to the absorption of the metals. Fibrogenic effects were detected after longer periods, involving high levels of oxyproline and lipids in the lung tissue during the second phase of the experiment. Increased lung mass is evidently linked to the formation of fibrous tissue and dust accumulation. As rats inhaling the 2mg/m3 concentration developed early functional and later organic damage, this level cannot be taken as an exposure limit.
||copper; respirable dust; non-ferrous metal industries; cadmium; mixed dust
||toxic effects; fibrogenic effects; animal experiments
||D - Periodical articles
||Dust, aerosols and related diseases
|Broad subject area(s)
Smelting and refining operations
Copper and compounds
Cadmium and compounds