|Document ID (ISN)||37450|
|ISSN - Serial title
||0025-7818 - Medicina del lavoro
|Convention or series no.
||Innocenti A., Franzinelli A., Sartorelli E.
||Longitudinal study of workers suffering from polyurethane asthma
||Studio longitudinale in lavoratori affetti da asma da resine poliuretaniche [in Italian]|
||May-June 1981, Vol.72, No.3, p.231-237. 43 ref.
||In 37 polyurethane production workers with isocyanate asthma, examinations carried out 40 months after exposure had ceased showed that asthmatic symptoms had disappeared in 32 workers but that chronic bronchitis had developed in 6. The progressive impairment of ventilatory function was evaluated by measuring the decrease in forced vital capacity (FVC) and FEV1 after exposure had ceased. Mean annual decreases of 86.3 and 67.7ml, respectively, were observed. Tolylene diisocyanate induces chronic and irreversible lung damage even after exposure is discontinued and impairment of FVC is greater than that of FEV1.
||chronic bronchitis; isocyanates; respiratory impairment; plastics converting industry; asthma
||polyurethanes; 2,6-tolylene diisocyanate; 2,4-tolylene diisocyanate; delayed effects; one-second forced expiratory volume; long-term study; maximal expiratory flow
||D - Periodical articles
|Broad subject area(s)
||Diseases of the respiratory system (except for pneumoconiosis & similar)