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Document ID (ISN)37444
CIS number 82-743
ISSN - Serial title 0301-0023 - Journal of the Society of Occupational Medicine
Year 1981
Convention or series no.
Author(s) Scarisbrick D.A., Martin J.V.
Title Biochemical changes associated with chloracne in workers exposed to tetrachlorazobenzene and tetrachlorazoxybenzene
Bibliographic information 4 Oct. 1981, Vol.31, No.4, p.158-163. 10 ref.
Abstract One year after mild chloracne developed in workers involved in the production of the herbicide Diuron, and its precursor 3,4-dichloraniline (DCA), abnormalities were found in the results of serial liver function tests and lipid profiles in some of the same workers. No significant abnormalities of liver function in the DCA-Diuron workers were found in an examination of the entire work force. A statistically significant increase in the mean triglyceride values was found and this was greater in those who had had chloracne. Mean cholesterol levels were also higher. The lipid values returned to normal as a result of a combined programme of improved occupational hygiene and personal health care.
Descriptors (primary) herbicides; pesticide production; biochemical effects; chloracne
Descriptors (secondary) diuron; lipids; 3,4-dichloroaniline; 3,3',4,4'-tetrachloroazobenzene; liver function tests; 3,3',4,4'-tetrachloroazoxybenzene
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Agricultural chemicals
Skin diseases
Chemical industry