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Document ID (ISN)37142
CIS number 82-416
ISSN - Serial title 0513-1731 - Yamaguchi Igaku (Yamaguchi Medical Journal)
Year 1981
Convention or series no.
Author(s) Hobara T., Kobayashi H., Higashihara E., Hirota H., Sakai T.
Title Health hazards due to exposure to low levels of toluene diisocyanate
Bibliographic information Mar. 1981, Vol.30, No.1, p.87-91. Illus. 13 ref.
Abstract Tolylene diisocyanate (TDI) concentrations in the workplace air of a plant producing polyurethane foam were measured. The serum IgE of 39 workers, and leucograms and pulmonary function tests in 20 workers showed: TDI workplace air concentrations were 0.017-0.021ppm, which was lower than the TLV. Serum IgE was significantly higher in TDI workers than in controls. Some of the workers with less than 1 year exposure to TDI showed significantly high serum IgE values. All these TDI-exposed workers with high serum IgE levels had symptoms of eosinophilia and obstructive ventilatory impairment. Summary and wording of all tables (serum IgE levels, leukograms, pulmonary function tests by flow-volume curve) in English.
Descriptors (primary) tolylene diisocyanate; subthreshold exposure; immunology; health impairment
Descriptors (secondary) obstructive ventilatory impairment; 2,6-tolylene diisocyanate; serological reactions; eosinophilia; exposure evaluation; 2,4-tolylene diisocyanate
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Isocyanates
Cyano compounds