|Document ID (ISN)||36747|
|ISSN - Serial title
||0004-1254 - Arhiv za higijenu rada i toksikologiju
|Convention or series no.
||Horvat Dj., Račić J., Rozgaj R.
||Frequency of sister chromatid exchanges in V79 cells of Chinese hamsters exposed to heavy metals
||Učestalost izmjena kromatida sestara u V79 stanica kineskog hrčka nakon izloženosti teškim metalima [in Serbocroatian]|
||1981, Vol.32, No.2, p.147-156. Illus. 26 ref.
||The sister chromatid exchange (SCE) method was used to investigate the mutagenic effect of heavy metals (Pb++, MN++, Ni++, Cd++). In vitro experiments with Chinese hamster V79 cells showed that Pb and Ni did not cause any significant change in SCE values, whereas exposure to Mn and Cd increased the number of changes; in particular, Cd had a marked mutagenic effect, doubling the number of exchanges after 2-h cell incubation.
||manganese; nickel; cadmium; chromosome changes; cytotoxic effects; lead
||in vitro experiments
||D - Periodical articles
|Broad subject area(s)
||Antifertility and prenatal effects
Genetic factors in reaction to exposures
Nickel and compounds
Cadmium and compounds
Lead and compounds