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CISDOC database

Document ID (ISN)36608
CIS number 81-1997
ISSN - Serial title 0003-9896 - Archives of Environmental Health
Year 1980
Convention or series no.
Author(s) Greenberg S.R.
Title Fluorescent studies on the potential existence of vascular metallic immune complexes
Bibliographic information May-June 1980, Vol.35, No.3, p.148-151. Illus. 17 ref.
Abstract In an acridine orange-stained preparation of the rat kidney, positive fluorescence was observed in the media of renal arterioles following long-term implantation of cadmium wire into the cortex, but was absent in animals similarly treated with copper wire or plastic. The presence of lymphocytic foci around the thickened vesels in Cd-containing kidneys, together with evidence of an association of RNA with immune complex formation, suggest that the vascular thickening in the presence of Cd ions is attributable to the mural location of a metallic-originated immune complex.
Descriptors (primary) renal diseases; cadmium; biological effects; immunology
Descriptors (secondary) immunobiological changes; detection by fluorescence; animal experiments
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Diseases of the kidney and the urinary system
Cadmium and compounds
Inorganic substances