| Document ID (ISN) | 36607 |
| CIS number |
81-1996 |
| ISSN - Serial title |
0003-9896 - Archives of Environmental Health |
| Year |
1980 |
| Convention or series no. |
|
| Author(s) |
Forni A., Sciamè A., Bertazzi P.A., Alessio L. |
| Title |
Chromosome and biochemical studies in women occupationally exposed to lead |
| Bibliographic information |
May-June 1980, Vol.35, No.3, p.139-145. 13 ref. |
| Abstract |
Blood lead levels and erythrocyte protoporphyrin and δ-aminolevulinic acid dehydratase activity of red blood cells were determined for 18 healthy females occupationally exposed to lead in the manufacture of electrical storage batteries and 12 female controls. Cytogenetic studies were performed on lymphocytes cultured for 2 and 3 days with phytohaemagglutinin. Significantly increased rates of metaphases with chromatid and chromosome aberrations, excluding gaps, were observed in the exposed vs. the control group at both culture times. The yield of abnormal metaphases was higher in the 3-day than in the 2-day cultures, in both exposed and control groups, but the difference was only moderately significant for controls and highly significant for those exposed. These results are consistent with those found for males. |
| Descriptors (primary) |
lead; biochemical effects; women; battery and dry cell manufacture; chromosome changes |
| Descriptors (secondary) |
comparative study; analysis of chromosome aberrations |
| Document type |
D - Periodical articles |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
|
| Browse category(ies) |
Inorganic substances
Lead and compounds
Genetic factors in reaction to exposures
Antifertility and prenatal effects
Manufacturing of electrical appliances and equipment
|
