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Document ID (ISN)36511
CIS number 81-1973
ISSN - Serial title 0300-9661 - Zentralblatt für Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene
Year 1980
Convention or series no.
Author(s) Schaller K.H., Gonzales J., Thürauf J., Schiele R.
Title Early screening for kidney damage in persons occupationally exposed to lead, mercury and cadmium
Original title Früherkennung von Nierenschäden bei beruflich gegenüber Blei, Quecksilber und Cadmium exponierten Personen [in German]
Bibliographic information Originale Reihe B, 171, 1980, No.4-5, p.320-335. Illus. 31 ref.
Abstract Report on medical examinations of 81 exposed workers in the metal trades and in manufacture of Ni-Cd storage batteries. To evaluate exposure, concentrations of these metals in blood and urine samples were determined. Renal excretion of certain proteins also served as an indicator of sub-clinical kidney damage. Description of analysis methods, results, and interpretation of results by comparison with those obtained by other authors. After relatively long-term exposure to Cd, characteristic β2-microglobulinuria and a high level of excreted total proteins can be observed; these phenomena are also observed, to a lesser extent, in persons exposed to Hg. Examination of persons exposed to lead did not show high levels of urinary protein excretion. Proposals are made for the urine analyses to be performed as part of a preventive medical examination in the case of exposure to Cd, and for limit concentrations of urinary and blood mercury to be observed in the case of exposure to Hg.
Descriptors (primary) mercury; lead; cadmium; chronic poisoning; exposure tests; renal damage
Descriptors (secondary) urinary excretion; proteinuria; biological threshold limits; urine monitoring; periodic medical examinations; blood monitoring; nephrotoxic effects
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Diseases of the kidney and the urinary system
Biological monitoring
Mercury and compounds
Cadmium and compounds
Lead and compounds
Inorganic substances