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Document ID (ISN)36491
CIS number 81-1567
ISSN - Serial title 0301-0279 - Revue française des maladies respiratoires
Year 1980
Convention or series no.
Author(s) Brambilla C., Brambilla E., Rigaud D., Perdrix A., Paramelle A., Forucy A.
Title Pneumoconiosis due to amorphous silica fume - Mineralogical and ultrastructural study of 6 cases
Original title Pneumoconiose aux fumées de silice amorphe - Etude minéralogique et ultrastructurale de 6 cas [in French]
Bibliographic information 1980, Vol.8, No.5, p.383-391. 9 ref.
Abstract Discussion of the toxicity of amorphous silica, reputed to be non-toxic, based on clinical, radiological, mineralogical and ultrastructural studies with 6 cases of pneumoconiosis in patients working in silicon foundries, with an exposure time of 5-35 years. In all but one case, symptoms were minimal or absent, with an interstitial syndrome and a restrictive syndrome. Histological findings showed an accumulation of alveolar and interstitial macrophages and the existence of fibrous interstitial micronodules. Amorphous silica fume is responsible for the occurrence of this pneumoconiosis.
Descriptors (primary) silica; pneumoconiosis; foundries; metal fumes; respirable dust
Descriptors (secondary) case study; lung biopsy; histopathology; long-term exposure
Document type D - Periodical articles
Subject(s) Dust, aerosols and related diseases
Broad subject area(s)
Browse category(ies) Pneumoconioses
Foundries, metalcasting and forging operations