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Document ID (ISN)36463
CIS number 81-1679
ISSN - Serial title 0019-8366 - Industrial Health
Year 1981
Convention or series no.
Author(s) Watanabe T., Endo A., Sato K., Ohtsuki T., Miyasaka M., Koizumi A., Ikeda M.
Title Mutagenic potential of styrene in man
Bibliographic information 1981, Vol.19, No.1, p.37-45. 36 ref.
Abstract Cytogenetic changes and cell-cycle kinetics were examined in the cultured lymphocytes of 16 workers exposed to styrene in two polyester fabrication workshops, where the airborne styrene concentrations were 2-211ppm in one and 30ppm in the other. The exposed workers showed no incrase in chromosomal aberrations or sister-chromatid exchange frequencies when compared with a control group. A slight decrease in the mitotic index and a slight inhibition of cell growth were detected. No relation was found between cytogenetic findings and styrene exposure intensity as determined by air analysis, personal sampling, or urinalysis for metabolites.
Descriptors (primary) mutagenic effects; plastics converting industry; styrene
Descriptors (secondary) hippuric acid; analysis of chromosome aberrations; phenylglyoxylic acid; mandelic acid
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Antifertility and prenatal effects
Aromatic hydrocarbons
Genetic factors in reaction to exposures