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CISDOC database
| Document ID (ISN) | 36461 |
| CIS number |
81-1678 |
| ISSN - Serial title |
0019-8366 - Industrial Health |
| Year |
1981 |
| Convention or series no. |
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| Author(s) |
Mithal R.K. |
| Title |
Histopathological studies with reference to chronic cadmium exposure in adrenal and spleen of common Indian ground squirrel |
| Bibliographic information |
1981, Vol.19, No.1, p.9-14. Illus. 8 ref. |
| Abstract |
Ground squirrels were injected intraperitoneally with a daily dose of cadmium acetate, at 1.0mg Cd/kg body weight, for 4, 5, 6 and 7 weeks, and the adrenals and spleen of exposed animals were compared with those of controls. The adrenals showed dilatation of sinusoids, fatty change in the cells of the cortex, hyaline-like mass in the medulla, haemorrhage adjacent to the medulla, circumscribed haemorrhage in the cortex, and congested blood vessels. The spleen showed congestion in blood vessels, thickening of vessel walls, and congestion and dilatation of sinusoids. The body weight gain of Cd-exposed animals was significantly lower than that of the controls, and the increase in spleen weight was significantly higher. |
| Descriptors (primary) |
splenic diseases; cadmium; histopathology; adrenal gland disorders |
| Descriptors (secondary) |
spleen; cadmium acetate; body weight; long-term exposure; chronic toxicity; animal experiments |
| Document type |
D - Periodical articles |
| Subject(s) |
Occupational pathology
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| Broad subject area(s) |
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| Browse category(ies) |
Inorganic substances
Endocrine diseases
Blood diseases
Cadmium and compounds
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