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Document ID (ISN)36383
CIS number 81-1669
Year 1980
Convention or series no.
Author(s) Marpeau S.
Title Styrene monomer - Current knowledge of toxicity and occupational hazards
Original title Le styrène monomère - Toxicité et risques professionnels actuellement connus [in French]
Bibliographic information Université de Paris V, Faculté de médecine Necker - Enfants-Malades, Paris, France, July 1980. 76p. 56 ref.
Abstract M.D. thesis reviewing current knowledge of styrene toxicity. It covers: structure; production; physical and chemical properties; experimental and human toxicity; metabolism; safety measures. Styrene oxide seems much more toxic than styrene. The main findings in animals, or animals and man, are skin and mucuous membrane irritation, pre-narcotic state, renal, haematological and pulmonary abnormalities and mutagenic potential via styrene oxide. The question of styrene carcinogenicity is raised. Recommendations: atmospheric concentrations of styrene below 100ppm, workplace ventilation, information of workers, personal protective equipment, pre-employment medical examinations, and limitation of working hours for women and young persons.
Descriptors (primary) styrene; styrene oxide; toxicology
Descriptors (secondary) mutagenic effects; France; metabolic process; irritation; thesis; medical prevention; narcotic effects; haematotoxic effects; nephrotoxic effects; pneumotoxic effects; limitation of exposure
Document type E - Books, reports, proceedings
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Ethylene oxide
Genetic factors in reaction to exposures
Aromatic hydrocarbons
Ethers