Document ID (ISN) | 36383 |
CIS number |
81-1669 |
Year |
1980 |
Convention or series no. |
|
Author(s) |
Marpeau S. |
Title |
Styrene monomer - Current knowledge of toxicity and occupational hazards |
Original title |
Le styrène monomère - Toxicité et risques professionnels actuellement connus [in French] |
Bibliographic information |
Université de Paris V, Faculté de médecine Necker - Enfants-Malades, Paris, France, July 1980. 76p. 56 ref. |
Abstract |
M.D. thesis reviewing current knowledge of styrene toxicity. It covers: structure; production; physical and chemical properties; experimental and human toxicity; metabolism; safety measures. Styrene oxide seems much more toxic than styrene. The main findings in animals, or animals and man, are skin and mucuous membrane irritation, pre-narcotic state, renal, haematological and pulmonary abnormalities and mutagenic potential via styrene oxide. The question of styrene carcinogenicity is raised. Recommendations: atmospheric concentrations of styrene below 100ppm, workplace ventilation, information of workers, personal protective equipment, pre-employment medical examinations, and limitation of working hours for women and young persons. |
Descriptors (primary) |
styrene; styrene oxide; toxicology |
Descriptors (secondary) |
mutagenic effects; France; metabolic process; irritation; thesis; medical prevention; narcotic effects; haematotoxic effects; nephrotoxic effects; pneumotoxic effects; limitation of exposure |
Document type |
E - Books, reports, proceedings |
Subject(s) |
Occupational pathology
|
Broad subject area(s) |
|
Browse category(ies) |
Ethylene oxide Genetic factors in reaction to exposures Aromatic hydrocarbons Ethers
|