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Document ID (ISN)36228
CIS number 81-1643
ISSN - Serial title Gigiena truda i professional'nye zabolevanija
Year 1980
Convention or series no.
Author(s) Malyševa M.V.
Title Delayed effects of benzene skin absorption in laboratory animals
Original title Opasnost' vozniknovenija otdalennyh posledstvij u laboratornyh životnyh pri postuplenii benzola čerez kožu [in Russian]
Bibliographic information June 1980, No.6, p.51-52. 11 réf.
Abstract Benzene application to the tail skin of rats (64 and 320 mg/kg) for 4 months produced changes in the morphological structure of the gonads in both males and females. Fertilisation potential in males and conception capacity in females were not impaired by prolonged skin absorption of benzene. Offspring of exposed animals were less viable than those of controls owing to lesions of certain organs.
Descriptors (primary) benzene; genetic effects; skin absorption
Descriptors (secondary) sequelae; gonadotropic effects; animal experiments
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Antifertility and prenatal effects
Aromatic hydrocarbons
Genetic factors in reaction to exposures