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Document ID (ISN)36023
CIS number 81-1371
ISSN - Serial title 0003-4509 - Annales pharmaceutiques françaises
Year 1979
Convention or series no.
Author(s) Delage C., Gualde N., Malinvaud G., Guichard C.
Title Identification of a genetic marker of predisposition to cadmium accumulation
Original title Mise en évidence d'un marqueur génétique prédisposant au stockage du cadmium. [in French]
Bibliographic information 1979, Vol.37, No.9-10, p.475-482. 18 ref.
Abstract Development of an atomic absorption technique for determining cadmium levels in biological fluids, especially blood, and its use in persons with non-occupational exposure (mean values: 5.5 ± 3.5mg/ml) and in workers employed in the manufacture of cadmium-rich dyes (mean value: 25 ± 20ng/ml). HLA phenotypes in the subjects examined were determined to study possible relations between specific phenotypes and predisposition to blood accumulation of cadmium. A3 group subjects have a particularly high predisposition to cadmium fixation in blood. In-vitro studies confirmed this predisposition.
Descriptors (primary) immunology; body retention; cadmium; individual susceptibility
Descriptors (secondary) determination in blood; antigens
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Cadmium and compounds
Inorganic substances