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Document ID (ISN)35463
CIS number 81-768
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1980
Convention or series no.
Author(s) Manson M.M.
Title Epoxides - is there a human health problem?
Bibliographic information Nov. 1980, Vol.37, No.4, p.317-336. 181 ref.
Abstract In this review, possible means of occupational and non-occupational exposure are discussed. In addition to the epoxides themselves, unsaturated compounds that may be metabolised in vivo to epoxides are included. Carcinogenicity and mutagenicity are discussed, with a brief outline of the mebatolism, binding to cell constituents, and DNA repair mechanisms. Interactions between different epoxides in vivo are considered.
Descriptors (primary) epoxy compounds; carcinogens
Descriptors (secondary) mutagenic effects; literature survey; metabolic process; round-up; animal experiments; synergism; carcinogenic effects; toxicity evaluation
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Ethylene oxide
Genetic factors in reaction to exposures
Ethers