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CISDOC database

Document ID (ISN)35425
CIS number 81-763
ISSN - Serial title 0355-3140 - Scandinavian Journal of Work, Environment and Health
Year 1980
Convention or series no.
Author(s) Norppa H., Sorsa M., Vainio H., Gr÷hn P., Heinonen E., Holsti L., Nordman E.
Title Increased sister chromatid exchange frequencies in lumphocytes of nurses handling cytostatic drugs.
Bibliographic information Dec. 1980, Vol.6, No.4, p.299-301. 14 ref.
Abstract 20 nurses in daily contact with cytostatic drugs (cyclophosphamide, 5-fluorouracil, methotrexate, adriamycin, cis-platinum(II) diamine dichloride) and 10 controls were studied. The oncology nurses had significantly higher sister chromatid exchange frequencies than the controls, and higher frequencies, although not significantly, than other nurses.
Descriptors (primary) pharmaceutical products; drugs; chromosome changes; genetic effects; hospitals
Descriptors (secondary) comparative study
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Antifertility and prenatal effects
Health care services
Genetic factors in reaction to exposures