|Document ID (ISN)||35333|
|ISSN - Serial title
||0009-0573 - Československß hygiena
|Convention or series no.
||Koudela K., Spazier K.
||Effects of dimethylformamide on human peripheral lymphocytes
||Vliv dimetylformamidu na lidskÚ perifernÝ lymfocyty [in Czech]|
||Nov. 1979, Vol.24, No.9, p.432-436. Illus. 10 ref.
||Cytogenetic analysis of peripheral lymphocytes from the blood of 3 healthy volunteers indicated that dimethylformamide induces mutations in somatic cells. Dimethylformamide had a mutagenic activity 3-4 times lower than that of thio-TEPA, a mutagen used in cancer therapy. The chromosome aberrations caused by dimethylformamide are consistent with the type of lesions caused by chemical mutagens.
||mutagenic effects; chromosome changes; toxic substances; dimethylformamide
||human experiments; cytogenetic studies; in vitro experiments
||D - Periodical articles
|Broad subject area(s)
||Antifertility and prenatal effects
Genetic factors in reaction to exposures