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Document ID (ISN)35233
CIS number 81-488
ISSN - Serial title 0025-7818 - Medicina del lavoro
Year 1980
Convention or series no.
Author(s) Nava C., Briatico-Vangosa G.
Title Isocyanate pathology: Methods of immunological diagnosis
Original title La patologia da isocianati: metodi di diagnosi immunologica [in Italian]
Bibliographic information July-Aug. 1980, Vol.71, No.4, p.305-311. Illus. 13 ref.
Abstract 250 workers exposed to diisocyanates were studied. Skin tests were done with conjugates of tolylene diisocyanate (TDI) or methylene diisocyanate (MDI) and human or egg albumin. There were reactions due to the presence of IgE and IgG immunoglobins, and cross reactions between the isocyanates. Exposure tests were also done in 45 cases: there were immediate and/or diphasic reactions in 55.6% and late reactions in 22.2%. The immunogenic and allergogenic properties of TDI and MDI were established.
Descriptors (primary) methylene diisocyanate; serological reactions; skin tests; tolylene diisocyanate
Descriptors (secondary) immunology; 2,4-tolylene diisocyanate
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Isocyanates
Cyano compounds