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CISDOC database

Document ID (ISN)35185
CIS number 81-480
ISSN - Serial title Cahiers de notes documentaires - Sécurité et hygiène du travail
Year 1980
Convention or series no.
Author(s) Siou G., Sourdeix D., Doinel A.
Title Mutagenic effects of benzene - 2. Influence of castration on male mouse susceptibility to the mutagenic effects of benzene
Original title Contribution à la connaissance de l'effet mutagène du benzène - 2. Action de la castration sur la sensibilité de la souris mâle à l'action mutagène du benzène. [in French]
Bibliographic information 4th quarter 1980, No.101, Note No.1286-101-80, p.531-534. 12 ref.
Abstract (For part 1, see CIS 80-1963). Benzene was administered orally to 8 groups of mice and a control group, including females, intact males, castrated males, and castrated males receiving testosterone. The sex-linked difference in sensitivity to benzene previously found disappered in the castrated males, and returned in those given testosterone subsequent to castration.
Descriptors (primary) benzene; mutagenic effects
Descriptors (secondary) sex-linked differences; animal experiments
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Antifertility and prenatal effects
Aromatic hydrocarbons
Genetic factors in reaction to exposures