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Document ID (ISN)35075
CIS number 81-463
ISSN - Serial title 0096-1736 - Journal of Occupational Medicine
Year 1980
Convention or series no.
Author(s) Buchet J.P., Roels H., Bernard A., Lauwerys R.
Title Assessment of renal function of workers exposed to inorganic lead, cadmium or mercury vapor.
Bibliographic information Nov. 1980, Vol.22, No.11, p.741-750. Illus. 27 ref.
Abstract Renal function of 148 cadmium workers, 63 mercury workers, and 25 inorganic lead workers was compared with 88 controls. Pb exposure (blood level up to 62µg/100ml) did not seem to affect renal function. High Cd exposure increases urinary excretion of low- and high-molecular-weight proteins and of tubular enzymes, especially in workers excreting more than 10µg Cd/g creatinine or with a blood level above 1µg/100ml. Hg exposure induces glomerular dysfunction, above all in workers with blood Hg above 3µg/ml and urinary Hg above 50µg/g creatinine. These Hg concentrations are proposed as biological threshold limits. Glomerular dysfunction induced by Cd and Hg might result from an autoimmune mechanism.
Descriptors (primary) mercury; cadmium; renal function tests; lead
Descriptors (secondary) urine monitoring; blood monitoring
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Inorganic substances
Mercury and compounds
Lead and compounds
Cadmium and compounds