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CISDOC database

Document ID (ISN)34528
CIS number 80-1963
ISSN - Serial title Cahiers de notes documentaires - Sécurité et hygiène du travail
Year 1980
Convention or series no.
Author(s) Siou G., Conan L., Doinel A.
Title Contribution to the study of the mutagenic effects of benzene - 1. Influence of sexual maturity on the sensitivity of mice to the mutagenic effect of benzene
Original title Contribution à la connaissance de l'effet mutagène du benzène - 1. Influence de la maturité sexuelle sur la sensibilité de la souris à l'action mutagène du benzène. [in French]
Bibliographic information 3rd quarter 1980, No.100, Note No.1268-100-80, p.395-397. 13 ref.
Abstract The Schmid experimental method was applied to mice aged 21 days and 5 weeks, and adult mice. The results show that there is no difference in reaction between male and female mice at 21 days, but that from an age of 5 weeks male mice are approximately twice as sensitive as female mice to the mutagenic effect of benzene.
Descriptors (primary) benzene; mutagenic effects
Descriptors (secondary) sex-linked differences; animal experiments
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Antifertility and prenatal effects
Aromatic hydrocarbons
Genetic factors in reaction to exposures