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Document ID (ISN)34166
CIS number 80-1646
Year 1979
Convention or series no.
Author(s) Cavelier C., Mereau P., Mur J.M.
Title Results of two epidemiological surveys with workers producing polyurethane foam mouldings.
Original title Résultats de deux enquêtes épidémiologiques chez des ouvriers fabriquant des pièces en mousse de polyuréthane. [in French]
Bibliographic information Edition INRS No.1103, Institut national de recherche et de sécurité, 30 rue Oliver-Noyer, 75680 Paris Cedex 14, France, Dec. 1979, p.103-151. Illus. 33 ref.
Abstract One study comprised 318 people working in factories manufacturing car trimmings and seats. The mean atmospheric concentration of isocyanates (TDI and MDI) was generally below the threshold limit value of 0.02ppm. There was no excessive incidence of bronchitic or asthmatic disorders or allergic reactions, especially in TDI exposed workers. Reduction in VC and in factor K (CO transfer/alveolar volume) was observed in the most highly exposed subjects. The second study involved 125 people working in a factory using massive quantities of TDI. Atmospheric concentrations of isocyanates were higher than the TLV on average, with peaks up to 100 times the TLV. There was an excessive incidence of subacute symptoms and syndromes of the restrictive type. Results are compared with those of other authors. A reduction of the TLV is recommended, and MDI should replace TDI.
Descriptors (primary) polyurethanes; plastics converting industry; functional respiratory disorders; isocyanates
Descriptors (secondary) threshold limit values; diphenylmethane diisocyanate; occupational health survey; 2,4-tolylene diisocyanate; exposure evaluation; 2,6-tolylene diisocyanate
Document type E - Books, reports, proceedings
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Isocyanates
Cyano compounds