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CISDOC database
| Document ID (ISN) | 33618 |
| CIS number |
80-1084 |
| ISSN - Serial title |
0340-0131 - International Archives of Occupational and Environmental Health |
| Year |
1980 |
| Convention or series no. |
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| Author(s) |
Van Roosmalen P.B., Klein A.L., Drummond I. |
| Title |
Simultaneous determination by gas chromatography of phenol, 2-chlorophenol, 2,4- and 2,6-dichlorophenol, 2,4,6-trichlorophenol, and 2,3,5,6-tetrachlorophenol in the urine of industrially exposed workers. |
| Bibliographic information |
Jan. 1980, Vol.45, No.1, p.57-62. Illus. 11 ref. |
| Abstract |
This method requires a minimum of sample treatment and has suitable sensitivity and selectivity for chlorophenols in the urine of workers exposed in the production of phenoxy herbicides and of pentachlorophenol. The phenolic compounds are separated by steam distillation, extracted into isopropyl ether, and analysed by gas chromatography directly, using flame ionization detectors. The detection limits in urine range from 0.1mg/l urine for phenol to 1mg/l for the di- and triphenols. The naturally occurring metabolites cresol and 4-heptanone are also isolated and can be quantified by this method. |
| Descriptors (primary) |
chlorophenols; urine monitoring; exposure tests |
| Descriptors (secondary) |
herbicides; phenol; pentachlorophenol; trichlorophenols; dichlorophenols; gas chromatography; determination in urine; urinary metabolites |
| Document type |
D - Periodical articles |
| Subject(s) |
Occupational pathology
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| Broad subject area(s) |
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| Browse category(ies) |
Alcohols
Biological monitoring
Phenols and phenolic compounds
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