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CISDOC database

Document ID (ISN)33303
CIS number 80-779
ISSN - Serial title 0355-3140 - Scandinavian Journal of Work, Environment and Health
Year 1979
Convention or series no.
Author(s) Holmberg P.C., Hernberg S.
Title Congenital defects and occupational factors - A comparison of different methodological approaches.
Bibliographic information Dec. 1979, Vol.5, No.4, p.328-332. 6 ref.
Abstract 120 mothers known to have been exposed to organic solvents, with children having congential central nervous system defects (for previous case-control study see CIS 79-1685) were followed up by a conventional analysis of occupational factors, to determine whether this method would provide the same information as the more laboroious interview method used previously. A further 102 mothers of children with oral defects were included in the study. Information on mothers' work outside the home, social group, and occupation, was ineffective for the purpose of discerning causative occupational factors for these malformations. The information on exposure to organic solvents could only be obtained by thorough history taking and inquiries about possible exposures at work.
Descriptors (primary) organic solvents; expectant mothers; teratogenic effects; genetic effects
Descriptors (secondary) embryotoxic effects; neurotoxic effects; comparative study; diseases of central nervous system; description of technique; anamnesis
Document type -
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Genetic factors in reaction to exposures
Antifertility and prenatal effects