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CISDOC database

Document ID (ISN)33127
CIS number 80-510
ISSN - Serial title 0003-0805 - American Review of Respiratory Disease
Year 1979
Convention or series no.
Author(s) Nelson L.A., Callerame M.L., Schwartz R.H.
Title Aspergillosis and atopy in cystic fibrosis.
Bibliographic information Oct. 1979, Vol.120, No.4, p.863-873. Illus. 47 ref.
Abstract 46 patients with cystic fibrosis (CF) were studied for colonisation and sensitisation by Aspergillus organisms. Aspergillus precicitins were found in 37% of CF patients; positive skin tests were found in 39%; atopy defined by skin test criteria was found in 46%. All of these findings were more common in patients with severe disease (P<0.05). CF patients had predominant mould sensitivity in contrast to predominant pollen sensitivity in a control group of asthmatic subjects. Serum IgE concentrations were increased in 22% of CF patients; 4 patients fulfilled the diagnostic criteria for allergic bronchopulmonary aspergillosis (ABPA) during the time of study and follow-up, and another patient had ABPA diagnosed before the study. The incidence of ABPA during a 2-year period in the CF population was 11%.
Descriptors (primary) Aspergillus moulds; aspergillosis; allergic respiratory disorders; immunology; pulmonary fibrosis
Descriptors (secondary) USA; case study; serological reactions; skin tests; hypersensitivity; survey
Document type -
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s)
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Mycoses
Bacterial and parasitic diseases
Allergies