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CISDOC database

Document ID (ISN)33081
CIS number 80-466
ISSN - Serial title 0040-6376 - Thorax
Year 1979
Convention or series no.
Author(s) Harries M.G., Burge P.S., Samson M., Taylor A.J.N., Pepys J.
Title Isocyanate asthma: respiratory symptoms due to 1,5-naphthylene diisocyanate.
Bibliographic information Dec. 1979, Vol.34, No.6, p.762-766. 12 ref.
Abstract Occupational asthma is reported in 3 workers exposed to 1,5-naphthylene diisocyanate (NDI), a hot curing agent used in manufacturing rubber. NDI was thought to be safer than tolylene or diphenylmethane diisocyanate on account of its higher melting point. Provocation tests indicated sensitisation to NDI. After 3 years, airways narrowing persisted in the 2 workers who remained exposed.
Descriptors (primary) naphthylene diisocyanate; synthetic rubber industry; allergic asthma
Descriptors (secondary) case study; hardeners; sensitization; inhalation tests; restrictive ventilatory impairment
Document type -
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Plastics industry
Cyano compounds
Chemical industry