| Document ID (ISN) | 33047 |
| CIS number |
80-460 |
| ISSN - Serial title |
0140-6736 - Lancet |
| Year |
1979 |
| Convention or series no. |
|
| Author(s) |
Mitelman F., Nilsson P.G., Brandt L., Alimena G., Montuoro A., Dallapiccola B. |
| Title |
Chromosomes, leukaemia, and occupational exposure to leukaemogenic agents. |
| Bibliographic information |
1 Dec. 1979, Vol.II, No.8153, p.1195-1196. 5 ref. |
| Abstract |
The study abstracted under CIS 80-459 was extended to a total of 156 patients with acute non-lymphocytic leukaemia (ANLL). Clonal chromosomal aberrations were significantly more common in exposed than non-exposed patients: 76% of exposed, 32% of non-exposed. 9 of the 12 patients with normal chromosomes were exposed to petroleum products or their combustion residues; 32 of 34 patients exposed to chemical solvents and insecticides had abnormal chromosomes. Possible causes of conflicting results with other studies are discussed. Prospective studies are in progress. |
| Descriptors (primary) |
leukaemogenic effects; chromosome changes; harmful substances; leukaemia |
| Descriptors (secondary) |
Sweden; petroleum products; Italy; ongoing research; organic solvents; pyrolysis products; survey; insecticides |
| Document type |
- |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
|
| Browse category(ies) |
Leukaemia
Genetic factors in reaction to exposures
Antifertility and prenatal effects
|
