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CISDOC database

Document ID (ISN)32701
CIS number 80-110
ISSN - Serial title 0003-0805 - American Review of Respiratory Disease
Year 1978
Convention or series no.
Author(s) Fink J.N., Schlueter D.P.
Title Bathtubs refinisher's lung: An unusual response to toluene diisocyanate.
Bibliographic information Nov. 1978, Vol.118, No.5, p.955-959. Illus. 24 ref.
Abstract Immunologic and inhalation challenge studies were performed on a 45 year-old patient engaged in bathtub refinishing who developed systemic and respiratory symptoms (cough, dyspnoea, myalgia, fever to 40░C) suggestive of hypersensitivity pneumonitis related to his occupation (the refinishing process involved the use of a catalyst containing tolylene diisocyanate). All clinical features of the disorder were reproduced by challenge. No immunologic mechanism could be identified. A change of occupation resulted in complete relief of symptoms. The patient had worn a mask when spraying the activated paint, but the premises were inadequately ventilated.
Descriptors (primary) catalysts; tolylene diisocyanate; allergic respiratory disorders; spray coating; work in confined spaces
Descriptors (secondary) case study; 2,4-tolylene diisocyanate; sensitization; inhalation tests; immunology
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Surface treatment
Cyano compounds
Confined spaces