|Document ID (ISN)||32701|
|ISSN - Serial title
||0003-0805 - American Review of Respiratory Disease
|Convention or series no.
||Fink J.N., Schlueter D.P.
||Bathtubs refinisher's lung: An unusual response to toluene diisocyanate.
||Nov. 1978, Vol.118, No.5, p.955-959. Illus. 24 ref.
||Immunologic and inhalation challenge studies were performed on a 45 year-old patient engaged in bathtub refinishing who developed systemic and respiratory symptoms (cough, dyspnoea, myalgia, fever to 40░C) suggestive of hypersensitivity pneumonitis related to his occupation (the refinishing process involved the use of a catalyst containing tolylene diisocyanate). All clinical features of the disorder were reproduced by challenge. No immunologic mechanism could be identified. A change of occupation resulted in complete relief of symptoms. The patient had worn a mask when spraying the activated paint, but the premises were inadequately ventilated.
||catalysts; tolylene diisocyanate; allergic respiratory disorders; spray coating; work in confined spaces
||case study; 2,4-tolylene diisocyanate; sensitization; inhalation tests; immunology
||Toxic and dangerous substances
|Broad subject area(s)
||Diseases of the respiratory system (except for pneumoconiosis & similar)