ILO Home
Go to the home page
Site map | Contact us Français | Español

CISDOC database

Document ID (ISN)32662
CIS number 80-211
ISSN - Serial title 0019-8366 - Industrial Health
Year 1979
Convention or series no.
Author(s) Koshi K.
Title Effects of fume particles from stainless steel welding on sister chromatid exchanges and chromosome aberrations in cultured chinese hamster cells.
Bibliographic information Mar. 1979, Vol.17, No.1, p.39-49. Illus. 16 ref.
Abstract The frequency of sister chromatid exchanges and chromosome aberrations increased with the fume dose (particle concentration up to 200µg/ml). Particles from manual metal arc (MMA) welding were some 100 times more powerful than those from metal inert gas (MIG) welding. Chromium solubility was about 60 times higher in MMA fume particles than in MIG particles. The supernatant from the suspension of both fumes contained small amounts of manganese, nickel, iron and magnesium. Exposure to the supernatant increased the frequency of sister chromatid exchanges and chromosome aberrations. It is suggested that dissolved hexavalent chromium may be involved in the cytotoxic effect of stainless steel welding fume.
Descriptors (primary) arc welding and cutting; chromosome changes; welding fumes; metal fumes
Descriptors (secondary) shielded-arc welding; manual arc welding; in vitro experiments; chromium; cell culture; dose-response relationship; cytotoxic effects
Document type -
Subject(s) Metal production and metalworking
Broad subject area(s)
Browse category(ies) Antifertility and prenatal effects
Welding and cutting
Genetic factors in reaction to exposures