| Document ID (ISN) | 31994 |
| CIS number |
79-1288 |
| ISBN(s) |
91-7464-040-2; 91-7464-041-0 |
| Year |
1978 |
| Convention or series no. |
|
| Author(s) |
Alexandersson R., Hedenstierna G., Lidums V. |
| Title |
Effects of exposure to cobalt - 3. Ventilatory capacity, distribution of inhaled gases and ventilatory obstruction during and after exposure - 4. Cobalt in blood and urine as exposure indicators |
| Original title |
Undersökningar över effekter av exposition för kobolt - 3. Ventilationsförmåga, distribution av inandningsgas och luftvägsavstängning under pågående arbete och efter expositionsuppehåll - 4. Koboltkoncentrationen i blod och urin som expositionsindikator [in Swedish] |
| Bibliographic information |
Arbete och hälsa - Vetenskaplig skriftserie 1979:7, 1979:8, Arbetarskyddsverket, Fack, 100 26 Stockholm, Sweden, 2 booklets, Nov. and Dec. 1978. 25 and 23p. Illus. 30 and 33 ref. |
| Abstract |
For Parts 1 and 2, see CIS 79-1287. In Part 3, lung function effects were studied in 155 workers and 74 controls. The workers were divided into exposure groups and examined by spirometry and single-breath nitrogen washout. Pulmonary function was impaired during the week in moderately and highly exposed workers; the function returned to normal in low-exposed subjects after a weekend. Exposures below the Swedish threshold limit value (0.1mg/m3) resulted in acute but subsiding airway obstruction. Part 4 describes the methods developed for the measure of cobalt in blood and urine. Cobalt (Co) was rapidly excreted in urine for high exposure; for low exposures, the excretion was relatively constant. Variations in blood concentrations were smaller, but followed exposure. The blood-urine concentration correlation on Friday afternoon was 0.82. When the average Co exposure for the whole week was compared with the concentration in urine, the correlation coefficient on Friday afternoon was 0.79 and for Monday morning 0.81; for blood, the respective correlations were 0.87 and 0.76. English summaries. |
| Descriptors (primary) |
cobalt; powder metallurgy; respirable dust; respiratory impairment; blood monitoring; urine monitoring; cemented carbides |
| Descriptors (secondary) |
tungsten carbide 1:1; exposure tests; obstructive ventilatory impairment |
| Document type |
E - Books, reports, proceedings |
| Subject(s) |
Dust, aerosols and related diseases
|
| Broad subject area(s) |
|
| Browse category(ies) |
Inorganic substances
Biological monitoring
Diseases of the respiratory system (except for pneumoconiosis & similar)
Metalworking industry
|
