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CISDOC database

Document ID (ISN)31976
CIS number 79-1424
ISSN - Serial title 0096-1736 - Journal of Occupational Medicine
Year 1979
Convention or series no.
Author(s) Karol M.H., Sandberg T., Riley E.J., Alarie Y.
Title Longitudinal study of tolyl-reactive IgE antibodies in workers hypersensitive to TDI.
Bibliographic information May 1979, Vol.21, No.5, p.354-358. 10 ref.
Abstract 3 workers with tolylene diisocyanate (TDI) sensitivity were evaluated for IgE antibodies over 13 months, using a radioallergosorbent test system. Antibody titres were elevated in 2 who experienced several bronchial hypersensitivity responses to TDI with or without cutaneous reactions during the study period. Antibody titres were low in a third subject who showed no such reactions during the study. In the absence of renewed TDI exposure, sensitive workers may have titres indistinguishable from those of non-sensitive TDI-workers.
Descriptors (primary) tolylene diisocyanate; serological reactions; hypersensitivity; immunology
Descriptors (secondary) 2,4-tolylene diisocyanate; allergic asthma; radioallergosorbent test; long-term study; diagnosis
Document type -
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Isocyanates
Cyano compounds