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CISDOC database

Document ID (ISN)31809
CIS number 79-1351
ISSN - Serial title 0340-7047 - Zentralblatt für Arbeitsmedizin, Arbeitsschutz und Prophylaxe
Year 1978
Convention or series no.
Author(s) Thiess A.M., Fleig I.
Title Research on chromosome changes in workers exposed to bis(2-ethylhexyl) phthalate (DOP)
Original title Chromosomenuntersuchungen bei Mitarbeitern mit Exposition gegenüber Di-2-äthylhexylphthalat (DOP) [in German]
Bibliographic information Dec. 1978, Vol.28, No.12, p.351-355. Illus. 22 ref.
Abstract DOP is used as a plasticiser in the production of non-rigid plastics. Technical data and diagram of production method, exposure of workers involved in DOP production in a chemicals plant. A study of chromosome changes was made in 10 workers with history of 10-30 years exposure to 0.0006-0.01ppm DOP. When compared to the results obtained with non-exposed workers, the results of the present research did not indicate high levels of chromosome changes, which precludes the existence of a mutagenicity hazad in DOP production.
Descriptors (primary) chemical industry; plasticizers; chromosome changes; bis(ethylhexyl) phthalate
Descriptors (secondary) exposure evaluation; analysis of chromosome aberrations; long-term exposure
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Antifertility and prenatal effects
Genetic factors in reaction to exposures
Esters and salts
Chemical industry