| Document ID (ISN) | 31513 |
| CIS number |
79-1046 |
| Year |
1978 |
| Convention or series no. |
|
| Author(s) |
Winell M. |
| Title |
Basic data for carcinogenicity evaluation - II. Some alkylating substances |
| Original title |
Underlag för utvärdering av carcinogena effekter - II. Några alkylerande ämnen [in Swedish] |
| Bibliographic information |
Undersökningsrapport 1978:20, Arbetarskyddsstyrelsen, Fack, 100 26 Stockholm, Sweden, 1978. 35p. 60 ref. |
| Abstract |
This report considers the chemical and physical properties, production and uses, methods of determination in air, acute toxicity, observed carcinogenicity in animals and man, mutagenicity, effects on reproduction and toxicokinetics of 4 alkylating substances: 1,2-dibromo-3-chloropropane (nemagon), epichlorohydrin, 1,2-dibromoethane (ethylene dibromide) and methyl iodide (iodomethane). As it is impossible to extrapolate TLVs from animal experiments, the author recommends that all exposure to these substances should be avoided, and that less harmful substances should be substituted for them. |
| Descriptors (primary) |
alkylating substances; carcinogens; dibromoethane; iodomethane; Nemagon; epichlorohydrin |
| Descriptors (secondary) |
mutagenic effects; toxic effects; Sweden; report; limitation of exposure; uses; animal experiments; gonadotropic effects; carcinogenic effects; determination in air; substitution |
| Document type |
E - Books, reports, proceedings |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Ethylene oxide
Genetic factors in reaction to exposures
Halogenated hydrocarbons
Ethers
|
