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CISDOC database
| Document ID (ISN) | 31388 |
| CIS number |
79-774 |
| Year |
1978 |
| Convention or series no. |
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| Title |
Criteria for a recommended standard - Occupational exposure to nitriles. |
| Bibliographic information |
DHEW (NIOSH) Publication No.78-212, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, Ohio 45226, USA, Sep. 1978. 155p. 127 ref. |
| Abstract |
Recommendations are made for the prevention of occupational disease due to mono- and dinitriles and cyanohydrins. The time-weighted average concentrations for up to a 10h workshift, 40h work week or ceiling concentrations based on a 15min sampling period are (mg/m3, ppm, type of limit given): acetonitrile (34, 10, TWA); propionitrile (14, 6, TWA); n-butyronitrile (22, 8, TWA); isobutyronitrile (22, 8, TWA); acetone cyanohydrin (4, 1, ceiling); glycolonitrile (5, 2, ceiling); malononitrile (8, 3, TWA); adiponitrile (18, 4, TWA); succinonitrile (20, 6, TWA); tetramethylsuccinonitrile (6, 1, ceiling). Other recommendations relate to medical surveillance, labelling and posting, personal protective equipment and clothing, information of personnel, work practices and control procedures, sanitation, monitoring and recordkeeping. The criteria on which the recommendations are based are discussed at some length under the following heads: biological effects (literature review, dose-response relations); environmental data; exposure control; development of standard; research needs. Procedures for sampling and analysis and first aid are given in appendices. |
| Descriptors (primary) |
threshold limit values; USA; limitation of exposure; toxicology; nitriles |
| Descriptors (secondary) |
literature survey; information of personnel; glycolonitrile; acetone cyanohydrin; adiponitrile; acetonitrile; propionitrile; butyronitrile; isobutyronitrile; malononitrile; succinonitrile; tetramethylsuccinonitrile; warning notices; personal protective equipment; safe working methods; dose-response relationship; biological effects; health service records; air sampling; determination in air; medical supervision; directive; welfare facilities |
| Document type |
F - Information notes, codes of practice, standards |
| Subject(s) |
Toxic and dangerous substances
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| Broad subject area(s) |
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| Browse category(ies) |
Occupational exposure limits
Cyano compounds
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