ILO Home
Go to the home page
Site map | Contact us Français | Español

CISDOC database

Document ID (ISN)31128
CIS number 79-780
ISSN - Serial title 0355-3140 - Scandinavian Journal of Work, Environment and Health
Year 1978
Convention or series no.
Author(s) Seppäläinen A.M., Husman K., Mårtenson C.
Title Neurophysiological effects of long-term exposure to a mixture of organic solvents.
Bibliographic information Dec. 1978, Vol.4, No.4, p.304-314. Illus. 48 ref.
Abstract The subjects in this study were 102 car painters and the control was an age-matched group of 102 railroad engineers. The main components of the mixture were toluene, xylene, butyl acetate and white spirit; mean concentration was 31,8% of the Finnish threshold limit value; the ranges of the components were 4-212%. Electroencephalograms (EEGs) were made of all the subjects, but electroneuromyograms of 59 painters and 53 engineers. Motor (MCV) and sensory conduction (SCV) velocities and motor distal latencies (MDL) were recorded from nerves in the upper and lower extremities. Abnormal EEGs occurred in 32 car painters and 37 controls. The frequency in both groups was higher than expected (10%). 26 painters had a complex of 4 common disturbance symptoms in the central nervous system (CNS); but only 12 engineers. 46% of the painters with this symptoms had an abnormal EEG, only 25% of those without the symptoms. Engineers did not show the tendency. Abnormally slow MCVs or SCVs and/or prolonged MDL occurred in 12 of the painters, but in none of the engineers. Objective signs of CNS involvement were minor.
Descriptors (primary) neurotoxic effects; service stations and repair shops; organic solvents; paint spraying
Descriptors (secondary) toluene; butyl acetate; white spirit; gluing; degreasing agents; long-term exposure; xylene; nervous conduction; electromyography; electroencephalography; vehicle repair and servicing
Document type -
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Surface treatment
Diseases of the nervous system
Road transportation