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CISDOC database

Document ID (ISN)30404
CIS number 78-1958
Year 1976
Convention or series no.
Author(s) Duprat P., Delsaut L., Gradisky D.
Title Irritative power of common acids and bases on the rabbit skin and eye mucosa
Original title Pouvoir irritant des acides et bases usuels sur la peau et les muqueuses oculaires du lapin. [in French]
Bibliographic information Notes scientifiques et techniques de l'INRS, No.10, Institut national de recherche et de sÚcuritÚ, 30 rue Olivier-Noyer, 75680 Paris Cedex 14, France, Aug. 1976. 63p. 27 ref.
Abstract Report on studies with various concentrations of ammonia, sodium and potassium hydroxides, and sulfuric, hydrochloric and chromic acids in aqueous solution based on Draizo's method, the official cosmetics testing method, and Kay and Calandra's method of interpretation. The nature, severity and course of the lesions caused by each product according to concentration is recorded, and findings obtained by other authors in animals and man are compared. Concentrations causing little or no irritation were determined, and skin and eye irritation scales established.
Descriptors (primary) irritants; bases, alkalis; mucous membranes; skin; acids
Descriptors (secondary) hydrochloric acid; sodium hydroxide; report; France; ammonia; eyes; animal experiments; sulfuric acid; potassium hydroxide; chromic acid; permissible levels
Document type E - Books, reports, proceedings
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Inorganic substances
Alkaline materials
Inorganic acids