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CISDOC database

Document ID (ISN)30324
CIS number 78-1993
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1978
Convention or series no.
Author(s) Sakurai H., Onodera M., Utsunomiya T., Minakuchi H., Iwai H., Matsumura H.
Title Health effects of acrylonitrile in acrylic fibre factories.
Bibliographic information Aug. 1978, Vol.35, No.3, p.219-225. 24 ref.
Abstract The relationship between exposure and biological effects of acrylonitrile (AN) was studied in 102 workers exposed for more than 5 years and in controls at 6 acrylic factories, classified into 3 groups according to AN exposure. Exposure in the group with the highest 8-h average was 4.2ppm, and in these workers the mean urinary AN concentration was 360µg/l and the mean urinary thiocyanate concentration 11.4mg/l. No health effects of AN were seen, except possibly slight liver damage in highly exposed workers. Carcinogenicity was not studied. Urinary AN and thiocyanate determinations may provide a useful estimate of exposure at levels below 5ppm.
Descriptors (primary) synthetic fibre industry; health impairment; acrylonitrile
Descriptors (secondary) hepatotoxic effects; long-term exposure; comparative study; urine monitoring; exposure tests
Document type -
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Cyano compounds