| Document ID (ISN) | 29867 |
| CIS number |
78-1374 |
| ISSN - Serial title |
Gigiena truda i professional'nye zabolevanija |
| Year |
1978 |
| Convention or series no. |
|
| Author(s) |
Bezsmertnyj V.E., Kurljandskij B.A. |
| Title |
Effect of long term exposure to low concentrations of carbon tetrachloride on the regulatory mechanisms for protein synthesis |
| Original title |
O dlitel'nom dejstvii četyrehhloristogo ugleroda v malyh koncentracijah na mehanizmy reguljacii sinteza belka [in Russian] |
| Bibliographic information |
Jan. 1978, No.1, p.33-37. Illus. 5 ref. |
| Abstract |
Exposure of white rats to low concentrations of carbon tetrachloride (CCl4) upset the mechanism for protein synthesis in the liver. Stopping the exposure started an increase in the amounts of ribonucleic acids in this organ, indicating an intensification of the recuperation process. The study of the protein synthesis regulating mechanism is useful for the determination of hepatotoxic effects. A revision of the Soviet threshold limit value of 20mg/m3 CCl4 in the workplace air is recommended. |
| Descriptors (primary) |
proteins; metabolic disturbances; carbon tetrachloride; hepatotoxic effects |
| Descriptors (secondary) |
threshold limit values; liver; long-term exposure; animal experiments; toxicology |
| Document type |
- |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Endocrine diseases
Halogenated hydrocarbons
|
