| Document ID (ISN) | 29211 |
| CIS number |
78-749 |
| ISSN - Serial title |
0096-1736 - Journal of Occupational Medicine |
| Year |
1978 |
| Convention or series no. |
|
| Author(s) |
Lauwerys R.R., Dath T., Lachapelle J.M., Buchet J.P., Roels H. |
| Title |
The influence of two barrier creams on the percutaneous absorption of m-xylene in man. |
| Bibliographic information |
Jan. 1978, Vol.20, No.1, p.17-20. 11 ref. |
| Abstract |
A method was developed to estimate skin absorption of m-xylene in humans. Unchanged m-xylene and total m-methylhippuric acid eliminated in the urine were measured over 24h. Absorption of m-xylene may vary by a factor of 2 in the same individual; interindividual variability is greater still. Mean absorption was 2.45µg/cm2. Barrier cream containing 10% silicone did not significantly affect absorption. A cream containing glycerol, stearates and oleostearates was not more effective. |
| Descriptors (primary) |
skin absorption; barrier creams; xylene |
| Descriptors (secondary) |
silicones; m-methylhippuric acid; human experiments; m-xylene; stearates |
| Document type |
- |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Skin protection
Aromatic hydrocarbons
|
