| Document ID (ISN) | 29149 |
| CIS number |
78-741 |
| ISSN - Serial title |
0340-7047 - Zentralblatt für Arbeitsmedizin, Arbeitsschutz und Prophylaxe |
| Year |
1977 |
| Convention or series no. |
|
| Author(s) |
Bettendorf U. |
| Title |
Occupationally-induced lung carcinomas following inhalation of alkylating compounds: bis(chloromethyl) ether and chloromethyl methyl ether |
| Original title |
Gewerblich induzierte Lungenkarzinome nach Inhalation alkylierender Verbindungen (Bischlormethyläther und Monochlormethyläther) [in German] |
| Bibliographic information |
June 1977, Vol.27, No.6, p.140-143. 13 ref. |
| Abstract |
Bis(chloromethyl) ether (BCME) and chloromethyl methyl ether (CMME) are used in the textile industry and in the manufacture of dyestuffs and insecticides on account of their alkylating effects. Animal experiments (skin application, subcutaneous injection, inhalation) showed the carcinogenicity of these substances. This article reviews 60 cases of lung carcinoma in workers with an average of 7.4 years of more or less intensive exposure to BCME or CMME. Significantly, the mean age of decease was 45 years. The carcinogenic effect of CMME was much less than that of BCME. |
| Descriptors (primary) |
alkylating substances; carcinogens; bis(chloromethyl) ether; lung cancer; chloromethyl methyl ether |
| Descriptors (secondary) |
mortality; animal experiments; dyestuff industry; pesticide production; textile industry |
| Document type |
- |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Diseases of the respiratory system (except for pneumoconiosis & similar)
Ethers
|
