| Document ID (ISN) | 28647 |
| CIS number |
78-152 |
| ISSN - Serial title |
0013-9351 - Environmental Research |
| Year |
1977 |
| Convention or series no. |
|
| Author(s) |
Heath C.W., Dumont C.R. |
| Title |
Chromosomal damage in men occupationally exposed to vinyl chloride monomer and other chemicals. |
| Bibliographic information |
Aug. 1977, Vol.14, No.1, p.68-72. 9 ref. |
| Abstract |
Measurements of chromosomal breakage were made in peripheral blood lymphocytes from 35 men exposed heavily, lightly or negligibly to vinyl chloride at plastics and tyre manufacturing plants. Breakage levels in all 3 groups were significantly higher than those in non-industrial control subjects. Breakage consisted mostly of simple chromatid gaps (86% of the aberrations). It appears that, in addition to vinyl chloride, other agents in these plants may cause cytogenetic damage to workers without it being possible to relate the damage to any of the wide range of chemicals (primarily solvents) to which rubber and plastics workers are exposed. |
| Descriptors (primary) |
vinyl chloride; tyre manufacturing industry; plastics industry; chromosome changes |
| Descriptors (secondary) |
lymphocytes; analysis of chromosome aberrations; cytogenetic studies |
| Document type |
- |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Chemical industry
Plastics industry
Genetic factors in reaction to exposures
Halogenated hydrocarbons
Antifertility and prenatal effects
Rubber industry
|
