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Document ID (ISN)28643
CIS number 78-186
ISSN - Serial title 0009-9309 - Clinical Toxicology
Year 1977
Convention or series no.
Author(s) Korsak R.J., Sato M.M.
Title Effects of chronic organophosphate pesticide exposure on the central nervous system.
Bibliographic information 1977, Vol.11, No.1, p.83-95. Illus. 17 ref.
Abstract Neuropsychological tests and EEG examinations were performed in 59 subjects occupationally exposed to organophosphate pesticides, including many also exposed to organochlorine or carbamate compounds. An index of chronic exposure to these pesticides was developed. Chronic exposure to clinically non-toxic levels of organophosphates has definite quantifiable effects on asymptomatic subjects. There was a relation between higher levels of exposure and frontal lobe impairment.
Descriptors (primary) neurotoxic effects; pesticides; organophosphorus compounds
Descriptors (secondary) nervous function tests; electroencephalographic changes; dose-response relationship; chronic poisoning; long-term exposure
Document type -
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Diseases of the nervous system
Agricultural chemicals