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CISDOC database

Document ID (ISN)28254
CIS number 77-1944
ISSN - Serial title Gigiena truda i professional'nye zabolevanija
Year 1976
Convention or series no.
Author(s) Korbakova A.I.
Title Comparative toxicity of chlorinated and fluorinated methane and ethane derivatives
Original title Sravnitel'naja toksičnost' hlorirovannyh i ftorirovannyh proizvodnyh gruppy metana i ėtana [in Russian]
Bibliographic information Nov. 1976, No.11, p.38-41. 7 ref.
Abstract Studies of Freon 22, 141 and 113 in mice. Introduction of a fluorine atom into the molecule markedly reduces the toxicity of these hydrocarbons, and modifies their effect on the organism, especially on long-term exposure to low concentrations. It is recommended that the highly toxic chlorinated compounds be replaced by fluorinated or chlorofluorinated ones. Comparative toxicity data on chlorinated, chlorofluorinated and fluorinated hydrocarbons.
Descriptors (primary) fluorinated hydrocarbons; chlorinated hydrocarbons; toxicology; molecular structure
Descriptors (secondary) literature survey; 1,2-dichloro-1-fluoroethane; 1,1,2-trichloro-1,2,2-trifluoroethane; comparative study; chlorofluorohydrocarbons; substitution; animal experiments; chlorodifluoromethane
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Inorganic substances
Halogenated hydrocarbons