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CISDOC database

Document ID (ISN)27401
CIS number 77-954
ISSN - Serial title 0041-008X - Toxicology and Applied Pharmacology
Year 1977
Convention or series no.
Author(s) Berteau P.E., Biermann A.H.
Title Respiratory deposition and early distribution of inhaled vegetable oil aerosols in mice and rats.
Bibliographic information Feb. 1977, Vol.39, No.2, p.177-183. 14 ref.
Abstract These aerosols were studied in order to determine the occupational hazards of pesticide formulations. Mice or rats were exposed to radio-labelled heptadecane in soya-bean oil and the amounts inhaled were determined from estimates of average respiratory minute volumes of the animals and the duration of exposure. The deposition and early distribution were calculated from the radioactivity. The amounts for mice and rats were, respectively: head 9.1, 3.1%; lung 3.8, 9.9%; stomach 59, 13%; esophagus 4.7, 0.4%; and duodenum 7.0, 1.9%. The amounts in the trachea were negligible in both species.
Descriptors (primary) pesticides; lung deposition; body retention; inhalation toxicity; aerosols
Descriptors (secondary) detection by radioactivity; animal experiments; inhalation
Document type -
Subject(s) Dust, aerosols and related diseases
Broad subject area(s)
Browse category(ies) Agricultural chemicals